PDRN skincare is the K-beauty trend of the moment, but you may not have expected us to launch our own soothing and firming PDRN serums. Those familiar with the ingredient already know that many brands use the original form of the ingredient: salmon PDRN. But as a 100% vegan skincare brand, we had to do a little extra brainstorming to put a plant-powered spin on it. After many tests and formulations, Haruharu Wonder Rose PDRN Soothing Serum and Rose PDRN Firming Serum were born.
Just like traditional PDRN serums, ours are inspired by the skin-rejuvenating effects of the original PDRN injection that has so many people booking flights to Seoul. But unlike an in-clinic PDRN treatment, you can get the multiple benefits of these serums at home. Of course, as topical formulas, they work a little differently from getting actual injections. Want to find out exactly what they can do for your skin? Below, our team shares the secrets behind our best PDRN serums, from how we made them to how you can use both in your daily routine. Let’s dive in.
What exactly is rose PDRN?
PDRN (also known as polydeoxyribonucleotide) is traditionally derived from salmon sperm DNA. Known for having a similar structure to human DNA, it’s said to promote tissue repair, stimulate collagen generation, and enhance skin firmness and elasticity when injected. When we brainstormed which alternative to use in our PDRN serum, we were most impressed by the results from rose-derived PDRN. Extracted from the stem cells of the Damascus rose, it aids the look of skin renewal and rejuvenation. We found that this ingredient was mild enough for even reactive skin types to use, while being naturally rich in antioxidants and amino acids.
To further boost its benefits, we carefully formulated it with other gentle-yet-effective ingredients. Keep reading to find out which ingredient pairing is right for you.
Which Rose PDRN serum is best for me?
PDRN skincare is trending for its renewing effects on skin texture and elasticity, as well as its compatibility with a wide range of skin types. We wanted to reflect that in both of our formulas.
If your skin is blemish-prone or easily stressed out, try our Rose PDRN Soothing Serum. It’s designed to soothe, hydrate, and help renew the look of your skin with every application—while remaining mild and barrier-friendly. Since we made it with a wide range of skin types in mind, we created a non-sticky, lightweight texture that feels like the most breathable cross between an ampoule and a gel cream. It’s perfect for layering with your other Haruharu Wonder favorites (more on that later) and leaves a naturally glowy finish that doesn’t feel greasy. This formula pairs rose PDRN with azelaic acid, which helps target concerns from redness, to rough texture, to acne and hyperpigmentation. We also included a trio of hydrators: sodium PCA, panthenol, and squalane. It’s been clinically proven to improve skin moisturizing by 88.93%, skin texture (roughness) by 11.02%, and visibly reduce redness by 21.84%.*
“My skin usually gets dry and irritated during winter, but the pairing of rose PDRN and azelaic acid feels so calming and hydrating,” says our team member Emineh. “My skin looked smooth and deeply hydrated when I woke up.”
*According to a clinical study conducted on 20 subjects after one application.
Or maybe your main skin goal is supporting elasticity and reducing the look of wrinkles. If that sounds like you, you’ll love Rose PDRN Firming Serum. This powerful formula blends our vegan PDRN with a complex of five peptides, 0.1% retinal, and adenosine. These ingredients are all known for their ability to help visibly plump, firm, and smooth—teaming up to help improve skin elasticity and target the appearance of fine lines and wrinkles. You’ll also notice that it feels completely different from our PDRN Soothing Serum; we infused it with a patented Phyto-Velvet Network for a creamy, velvety finish that feels luxurious while remaining weightless and non-sticky. It’s been clinically proven to improve periorbital wrinkles by 20.372% and skin elasticity by 23.151%.** It’s also clinically proven to temporarily improve pore area by 54.855%.**
“The PDRN Firming Serum has really done wonders for making my skin feel bouncier and a lot more hydrated,” says our team member Claire. “I've also noticed a smoother base when applying makeup the next day.”
**According to a clinical study conducted on 20 subjects after four weeks of use.
How to Use Rose PDRN Serums in Your Skincare Routine
Do both formulas sound tempting to you? Good news, you can use them together in your routine for maximum rose PDRN skin benefits. If you’re pairing them, grab our Soothing Serum in the morning and Firming Serum in the evening. Because the latter contains retinal, which can increase UV sensitivity, we recommend keeping it in your evening skincare routine and always following with sunscreen in the morning.
To complement the calming effects of our PDRN Soothing Serum, we personally like to pair it with other mild formulas like Black Rice Hyaluronic Toner for Sensitive Skin. Or, you can concentrate on its pore-clarifying, blemish-fighting effects with Triple AHA Gentle Cleansing Gel and 5% Niacinamide Radiance Gel Cream.
Our PDRN Firming Serum pairs great with other slow-aging best sellers like Botanical 2GF Wonderful Ampoule and Bakuchiol Eye Cream. They’re formulated to gradually deliver a youthful glow without overloading your skin with harsh ingredients.
“The soothing serum keeps my skin calm and hydrated during the day while the firming formula works overnight to smooth,” says our team member Jade. “I’ve seen a real improvement in my dark spots and overall glow.”
Call it your must-have skin combo of 2026. Grab the full routine below and tag us on Instagram @haruharuwonder_official so we can see your revitalized results.
Meet the Author
Haruharu Wonder contributor Sarah Y. Wu has a decade of experience in the industry as a beauty editor, copy director, and brand consultant. Her bylines have appeared in outlets including Teen Vogue, Forbes, Allure, Marie Claire, Glamour, NYLON, Bustle, The Zoe Report, Vogue, WWD, and Byrdie. She’s also the copywriter and copy director for some of your favorite skincare, fragrance, and makeup brands. While she’s tried thousands of products over the course of her career, she’ll always save a spot in her beauty routine for Haruharu Wonder’s Black Rice Bakuchiol Eye Cream and Centella Sunflower Makeup-Melting Cleansing Balm. Connect with her on Instagram @say.wu.
Which PDRN Serum Is Best for My Skin Type?
PDRN skincare is the K-beauty trend of the moment, but you may not have expected us to launch our own soothing and firming PDRN serums. Those familiar with the ingredient already know that many brands use the original form of the ingredient: salmon PDRN. But as a 100% vegan skincare brand, we had to do a little extra brainstorming to put a plant-powered spin on it. After many tests and formulations, Haruharu Wonder Rose PDRN Soothing Serum and Rose PDRN Firming Serum were born.
Just like traditional PDRN serums, ours are inspired by the skin-rejuvenating effects of the original PDRN injection that has so many people booking flights to Seoul. But unlike an in-clinic PDRN treatment, you can get the multiple benefits of these serums at home. Of course, as topical formulas, they work a little differently from getting actual injections. Want to find out exactly what they can do for your skin? Below, our team shares the secrets behind our best PDRN serums, from how we made them to how you can use both in your daily routine. Let’s dive in.
What exactly is rose PDRN?
PDRN (also known as polydeoxyribonucleotide) is traditionally derived from salmon sperm DNA. Known for having a similar structure to human DNA, it’s said to promote tissue repair, stimulate collagen generation, and enhance skin firmness and elasticity when injected. When we brainstormed which alternative to use in our PDRN serum, we were most impressed by the results from rose-derived PDRN. Extracted from the stem cells of the Damascus rose, it aids the look of skin renewal and rejuvenation. We found that this ingredient was mild enough for even reactive skin types to use, while being naturally rich in antioxidants and amino acids.
To further boost its benefits, we carefully formulated it with other gentle-yet-effective ingredients. Keep reading to find out which ingredient pairing is right for you.
Which Rose PDRN serum is best for me?
PDRN skincare is trending for its renewing effects on skin texture and elasticity, as well as its compatibility with a wide range of skin types. We wanted to reflect that in both of our formulas.
If your skin is blemish-prone or easily stressed out, try our Rose PDRN Soothing Serum. It’s designed to soothe, hydrate, and help renew the look of your skin with every application—while remaining mild and barrier-friendly. Since we made it with a wide range of skin types in mind, we created a non-sticky, lightweight texture that feels like the most breathable cross between an ampoule and a gel cream. It’s perfect for layering with your other Haruharu Wonder favorites (more on that later) and leaves a naturally glowy finish that doesn’t feel greasy. This formula pairs rose PDRN with azelaic acid, which helps target concerns from redness, to rough texture, to acne and hyperpigmentation. We also included a trio of hydrators: sodium PCA, panthenol, and squalane. It’s been clinically proven to improve skin moisturizing by 88.93%, skin texture (roughness) by 11.02%, and visibly reduce redness by 21.84%.*
“My skin usually gets dry and irritated during winter, but the pairing of rose PDRN and azelaic acid feels so calming and hydrating,” says our team member Emineh. “My skin looked smooth and deeply hydrated when I woke up.”
*According to a clinical study conducted on 20 subjects after one application.
Or maybe your main skin goal is supporting elasticity and reducing the look of wrinkles. If that sounds like you, you’ll love Rose PDRN Firming Serum. This powerful formula blends our vegan PDRN with a complex of five peptides, 0.1% retinal, and adenosine. These ingredients are all known for their ability to help visibly plump, firm, and smooth—teaming up to help improve skin elasticity and target the appearance of fine lines and wrinkles. You’ll also notice that it feels completely different from our PDRN Soothing Serum; we infused it with a patented Phyto-Velvet Network for a creamy, velvety finish that feels luxurious while remaining weightless and non-sticky. It’s been clinically proven to improve periorbital wrinkles by 20.372% and skin elasticity by 23.151%.** It’s also clinically proven to temporarily improve pore area by 54.855%.**
“The PDRN Firming Serum has really done wonders for making my skin feel bouncier and a lot more hydrated,” says our team member Claire. “I've also noticed a smoother base when applying makeup the next day.”
**According to a clinical study conducted on 20 subjects after four weeks of use.
How to Use Rose PDRN Serums in Your Skincare Routine
Do both formulas sound tempting to you? Good news, you can use them together in your routine for maximum rose PDRN skin benefits. If you’re pairing them, grab our Soothing Serum in the morning and Firming Serum in the evening. Because the latter contains retinal, which can increase UV sensitivity, we recommend keeping it in your evening skincare routine and always following with sunscreen in the morning.
To complement the calming effects of our PDRN Soothing Serum, we personally like to pair it with other mild formulas like Black Rice Hyaluronic Toner for Sensitive Skin. Or, you can concentrate on its pore-clarifying, blemish-fighting effects with Triple AHA Gentle Cleansing Gel and 5% Niacinamide Radiance Gel Cream.
Our PDRN Firming Serum pairs great with other slow-aging best sellers like Botanical 2GF Wonderful Ampoule and Bakuchiol Eye Cream. They’re formulated to gradually deliver a youthful glow without overloading your skin with harsh ingredients.
“The soothing serum keeps my skin calm and hydrated during the day while the firming formula works overnight to smooth,” says our team member Jade. “I’ve seen a real improvement in my dark spots and overall glow.”
Call it your must-have skin combo of 2026. Grab the full routine below and tag us on Instagram @haruharuwonder_official so we can see your revitalized results.
Meet the Author
Haruharu Wonder contributor Sarah Y. Wu has a decade of experience in the industry as a beauty editor, copy director, and brand consultant. Her bylines have appeared in outlets including Teen Vogue, Forbes, Allure, Marie Claire, Glamour, NYLON, Bustle, The Zoe Report, Vogue, WWD, and Byrdie. She’s also the copywriter and copy director for some of your favorite skincare, fragrance, and makeup brands. While she’s tried thousands of products over the course of her career, she’ll always save a spot in her beauty routine for Haruharu Wonder’s Black Rice Bakuchiol Eye Cream and Centella Sunflower Makeup-Melting Cleansing Balm. Connect with her on Instagram @say.wu.